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MORE CELLS, BETTER CELLS

UM171 delivers greater doses of functional cells by expanding primitive HSCs from any source and counteracting the attributes of older or manipulated cells

UM171: A MULTILEVEL SOLUTION FOR CELL THERAPY

If you wish to use UM171 for clinical or commercial manufacturing, please contact info@excellthera.com to enquire about the GMP formulation.

UM171 MECHANISM OF ACTION

UM171 FOR CELL & GENE THERAPIES

PURCHASE UM171

UM171 0.5mg

$703.66 CAD
$703.66 CAD
Sale Sold out

UM171 is a proprietary and patented small molecule for ex vivo use with a first-in-class mechanism of action involved in the expansion and metabolic fitness of Hematopoietic Stem and Progenitor Cells (HSPCs).

Certain Terms & Conditions apply to the purchase and use of the UM171 molecule, and the limited license thereunder does not allow the following uses:

1) any commercial use (research use only);

2) any use in humans (or in the manufacturing of a product used in humans);

If you wish to use UM171 for any of the foregoing, please contact info@excellthera.com to enquire about licensing opportunities.

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Select Publications

  • UM171: Improving Hematopoietic Stem Cells for Enhanced Cell and Gene Therapies

    White Paper

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  • Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study

    The Lancet Haematology

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  • Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

    Science

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  • UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex

    Cell Stem Cell

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